Inferring gene networks from discrete expression data
نویسندگان
چکیده
منابع مشابه
Inferring gene networks from discrete expression data.
The modeling of gene networks from transcriptional expression data is an important tool in biomedical research to reveal signaling pathways and to identify treatment targets. Current gene network modeling is primarily based on the use of Gaussian graphical models applied to continuous data, which give a closed-form marginal likelihood. In this paper, we extend network modeling to discrete data,...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2013
ISSN: 1468-4357,1465-4644
DOI: 10.1093/biostatistics/kxt021